Blogs the emissions of “heat not burn” tobacco products

  • April 18, 2021


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the emissions of “heat not burn” tobacco products

the emissions of “heat not burn” tobacco products

Consumers of combustible cigarettes are exposed to many different toxicologically relevant substances associated with negative health effects. Newly developed “heat not burn” (HNB) devices are able to contain lower levels of Harmful and Potentially Harmful Constituents (HPHCs) in their emissions compared to tobacco cigarettes. However, to develop toxicological risk assessment strategies, further independent and standardized investigations addressing HPHC reduction need to be done. Therefore, we generated emissions of a commercially available HNB product following the Health Canada Intense smoking regimen and analyzed total particulate matter (TPM), nicotine, water, aldehydes, and other volatile organic compounds (VOCs) that are major contributors to health risk. We show that nicotine yield is comparable to typical combustible cigarettes, and observe substantially reduced levels of aldehydes (approximately 80–95%) and VOCs (approximately 97–99%). Emissions of TPM and nicotine were found to be inconsistent during the smoking procedure. Our study confirms that levels of major carcinogens are markedly reduced in the emissions of the analyzed HNB product in relation to the conventional tobacco cigarettes and that monitoring these emissions using standardized machine smoking procedures generates reliable and reproducible data which provide a useful basis to assess exposure and human health risks.To get more news about Heat not burn, you can visit official website.
Tobacco consumption remains one of today’s major health hazards and was responsible for more than one in ten deaths in the year 2015 (GBD 2015 Tobacco Collaborators 2017). Consequently, tobacco control was strengthened by multiple measures in recent years, partly driven by implementation of the WHO Framework Convention on Tobacco Control (FCTC) (World Health Organization 2018). One strategy of tobacco companies to adapt to growing public and political pressure for further restrictions is the development of modified risk products or alternate tobacco products that are implied to be less hazardous. These claims are often based on reduced toxicant levels in the emissions, although these data cannot be directly translated into a health risk reduction. Notably, toxicant reduction strategies had also been proposed by WHO (World Health Organization 2014), opening discussions about feasibility of benefits for both smoking populations and individual smokers.

In principle, the conventional cigarettes are highly engineered products. A burning cigarette can be regarded as a connection of endo- and exothermic combustion systems (Baker et al. 2004). Yet, it gains complexity, since multiple mechanisms affect the generation of smoke (Muramatsu 2005). Smoke constituents are generated according to a temperature gradient depending on exothermic combustion within the burning tip. During puffs, temperatures can reach up to 950 °C. The majority of compounds, however, are formed in endothermic reactions within the adjacent pyrolysis-distillation zone where temperatures decrease from approximately 600 to 200 °C (Baker et al. 2004). Cigarette smoke consists of approximately 4800 compounds (Rodgman and Green 2003). At least 69 carcinogens had been identified by the year 2000 (Hoffmann et al. 2001) with an update to 98 hazardous components in 2011 (Talhout et al. 2011). Fowles and Dybing proposed an approach for prioritization of tobacco smoke constituents by applying toxicological risk assessment methods. They identified 1,3-butadiene and other substances like acetaldehyde as major contributors to cancer risk and thus suggested that harm reduction efforts should set a special focus on volatile organic compounds (Fowles and Dybing 2003).



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